Optimizing regulatable gene expression using adenoviral vectors
نویسندگان
چکیده
منابع مشابه
Construction of a regulatable cancer-specific adenoviral expression system using human telomerase reverse transcriptase gene promoter.
We constructed a novel cancer-specific regulatable adenoviral expression system comprising two vectors: one expressing rtTA, a reverse tetracycline transactivator regulated by the human telomerase reverse transcriptase (hTERT) gene promoter, the other expressing the target gene regulated by the tetracycline response element (TRE). rtTA transactivates target gene expression in the presence of do...
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ژورنال
عنوان ژورنال: Experimental Physiology
سال: 2004
ISSN: 0958-0670
DOI: 10.1113/expphysiol.2004.028209